Journal: eNeuro

Article Title: Capillary-Based and Stokes-Based Trapping of Serial Sections for Scalable 3D-EM Connectomics

doi: 10.1523/ENEURO.0328-19.2019

Figure Lengend Snippet: CAD model with finite element analysis. A , Isometric view of the trapping device designed in SolidWorks. This model has a trap width of 3.0 mm and a trap height of 0.5 mm. Scale bar: 3 mm. B , Top view of Young–Laplace equation solution domain. The domain is split symmetrically along the centerline, with the left side showing the finite element mesh and the right side showing the finite element solution for the interfacial height. C , Photograph of experimental setup with inset showing the induced curvature between the trapping posts. The trapping device is shown installed in the waterboat with water filled to appropriate height for sectioning. Air needles are mounted on the distal end of the waterboat using a custom fixture, which provide the hydrodynamic forces. A metal tube is shown protruding from the distal end of the waterboat used for modulating water level. Scale bar: 5 mm.

Article Snippet: Section trapping devices were designed using computer-aided design (CAD) software (SolidWorks).

Techniques:

Journal: Frontiers in Veterinary Science

Article Title: A 3-Dimensional Printed Patient-Specific Surgical Guide to Facilitate Transsphenoidal Hypophysectomy in Dogs

doi: 10.3389/fvets.2022.930856

Figure Lengend Snippet: (A) Sagittal section of the skull visualised with the CAD software Netfabb professional (rostral is to the left in the figure); cortical surfaces appear in yellow and the 3-dimensional printed guide in place is in grey: the distance between the vomer and the rostral aspect of the burring window depicted by the guide (A1) was measured by drawing a vertical line from the tip of the vomer to basisphenoid and another line, perpendicular to the first and extending to the rostral margin of the surgical guide; (B) dorsal view of the skull and surgical guide in place, visualised with the CAD software: the length (B1) and the width (C1) of the burring window into the basisphenoid first cortical bone layer appear as the green and blue double head dashed arrows, respectively; (C) the length of bone to remove from the inner cortical layer of the basisphenoid bone (red arrows) forming the sella turcica was defined to match that of the outer cortical layer to burr; (D) light blue line chosen to be no longer than the tuberculum sellae and the dorsum sellae ); (E) the length of inner and outer cortical layers to be removed where defined as equal; (F) sagittal reconstructed post-operative post-contrast CT image obtained to assess completeness of the hypophysectomy; note the signal void region suggesting presence of air.

Article Snippet: For each case, the CT DICOM images from a medical imaging software (Osirix, Pixmeo, SARL; Geneva, Switzerland) ( ) were exported to a computer aided design (CAD) software (Netfabb professional, Netfabb GmbH: Parsberg, Germany) and a surface rendered virtual 3D model of the skull was created, which also allowed to 3D print the skull ( ).

Techniques: Software